Combine Twist target enrichment with long read sequencing to efficiently sequence important genomic regions at scale. Pre-designed Twist Alliance panels enable researchers to capture target regions in a cost-effective and high throughput manner. Customers can also develop fully customizable and scalable panels with their own designs.
Panels Built for Long Read Sequencing Platforms
Probes optimized for high uniformity and sequencing efficiency
Balanced coverage across difficult-to-sequence or difficult–to-map regions
Custom panels with cost-effective and flexible scaling
Long Read Sequencing at Scale
Protocols optimized for long fragment enrichment
Pack more samples in a single sequencing run
Study targeted regions across large cohorts
Accurate Variant Calling
High accuracy variant calling of SNPs, SVs and indels
Unambiguous haplotype resolution and long-range phasing
Compatible with both Oxford Nanopore and PacBio long read platforms
Twist Alliance Dark Genes Panel
Enables sequencing of genes that are difficult or impossible to fully sequence with short read technology.
- Targets 389 genes (20 Mb)
- Key targets include GBA, SMN1/2
Full-gene phasing and no coverage gap in the GBA gene
Twist Alliance Long-Read PGx Panel
Focus on important genes in pharmacogenomics that are critical to drug metabolism and patient therapeutic response.
- Targets 49 genes (2 Mb)
- Key targets include CYP2D6, HLA-A, HLA-B
Accurate star allele calling at CYP2D6
Poster
Protocol
Webinar
Data Files
