The mouse is an extremely important model system for studying genetic variation, tumor mutations, and phenotypic outcomes as well as the therapeutic effect of pharmaceutical agents. As genetic variant databases are continuously updated, the Twist Mouse Exome panel is thoughtfully designed and built from the most current databases. When combined with Twist’s expanding portfolio of library preparation and enrichment reagents, the complete toolset allows researchers to achieve industry-leading coverage across target regions while optimizing sequencing cost and sample throughput.
The mouse is an extremely important model system for studying genetic variation, tumor mutations, and phenotypic outcomes as well as the therapeutic effect of pharmaceutical agents. As genetic variant databases are continuously updated, the Twist Mouse Exome panel is thoughtfully designed and built from the most current databases. When combined with Twist’s expanding portfolio of library preparation and enrichment reagents, the complete toolset allows researchers to achieve industry-leading coverage across target regions while optimizing sequencing cost and sample throughput.
With 5-Gb sequencing, the narrow variance and mode of the coverage distribution (left) reduces both the number of bases found below the targeted level of coverage (right) and the over- and under-sequencing from the typically skewed coverage associated with poorer uniformity. This is aided by the balanced capture profile across a much wider range of target %GC content.
Picard metrics of the Twist Mouse Exome Kit with two strains of mouse. Data obtained with 5 Gb (135x) sequencing.
With 5-Gb sequencing, the narrow variance and mode of the coverage distribution (left) reduces both the number of bases found below the targeted level of coverage (right) and the over- and under-sequencing from the typically skewed coverage associated with poorer uniformity. This is aided by the balanced capture profile across a much wider range of target %GC content.
Picard metrics of the Twist Mouse Exome Kit with two strains of mouse. Data obtained with 5 Gb (135x) sequencing.
102035
Twist Mouse Exome, 2 Reactions, Kit102036
Twist Mouse Exome, 12 Reactions, Kit102037
Twist Mouse Exome, 96 Reactions, KitWorkflow Step
Target EnrichmentFormat
dsDNAPanel size
37.7 MbContent
Mouse protein coding genesDesign Databases
RefSeqThe Twist Mouse Exome Panel is for research use only, and subject to additional use restrictions as set forth in Twist’s Supply Terms and Conditions.
102035
Twist Mouse Exome, 2 Reactions, Kit102036
Twist Mouse Exome, 12 Reactions, Kit102037
Twist Mouse Exome, 96 Reactions, KitWorkflow Step
Target EnrichmentFormat
dsDNAPanel size
37.7 MbContent
Mouse protein coding genesDesign Databases
RefSeqThe Twist Mouse Exome Panel is for research use only, and subject to additional use restrictions as set forth in Twist’s Supply Terms and Conditions.
Product Sheet
Protocol
