Quickly Generate High-Diversity, High-
Quality Molecules Inspired by the Human
Repertoire
Best-In-Class Synthetic Libraries Powered by Twist Technology
We are writing the future of biologics discovery with a best-in-class platform, our Library of Libraries, for hard-to-drug targets. Our collection of 17+ off-the-shelf libraries enables multiple pathways of discovery for your drug target of interest. We use our precision DNA synthesis technology to focus explicitly on the sequence space that will most benefit you and remove sequences associated with downstream developability and manufacturing liabilities.
Browse Our Library of Libraries
Quickly Generate High-Diversity, High-
Quality Molecules Inspired by the Human
Repertoire
Best-In-Class Synthetic Libraries Powered by Twist Technology
We are writing the future of biologics discovery with a best-in-class platform, our Library of Libraries, for hard-to-drug targets. Our collection of 17+ off-the-shelf libraries enables multiple pathways of discovery for your drug target of interest. We use our precision DNA synthesis technology to focus explicitly on the sequence space that will most benefit you and remove sequences associated with downstream developability and manufacturing liabilities.
Browse Our Library of Libraries
Uncover Hits Against Virtually Any Target
Expand Your Discovery Opportunities
Our pre-constructed, validated phage display libraries are built using our precision DNA writing technology, allowing us to remove motifs that can lead to downstream manufacturing liabilities and focus only on the applicable sequence space. Twist Bioscience has designed multiple general, naïve, and target-focused libraries with diversities of 1010, giving you a multifaceted approach to your next discovery project.
Fast Antibody Discovery
Our collection of off-the-shelf libraries enables you to quickly identify high-quality leads against your target of interest using multiple strategies in only a few months. Libraries are available in various VHH, Fab, and scFv formats. These libraries can be leveraged to develop monoclonal antibodies, bi- or multi-specifics, and chimeric antigen receptors (CARs) for CAR-T cell therapy.
A Proven Discovery Engine
Internal discovery efforts using the library of libraries have led to the generation and optimization of lead antibody agonists, antagonists, and binders, with robust pre-clinical data packages. Our fully-humanized antibodies and VHH nanobodies are available for licensing. They make it possible to drug high-value targets in broad therapeutic areas, including immuno-oncology, oncology, metabolic diseases, and more.
Uncover Hits Against Virtually Any Target
Expand Your Discovery Opportunities
Our pre-constructed, validated phage display libraries are built using our precision DNA writing technology, allowing us to remove motifs that can lead to downstream manufacturing liabilities and focus only on the applicable sequence space. Twist Bioscience has designed multiple general, naïve, and target-focused libraries with diversities of 1010, giving you a multifaceted approach to your next discovery project.
Fast Antibody Discovery
Our collection of off-the-shelf libraries enables you to quickly identify high-quality leads against your target of interest using multiple strategies in only a few months. Libraries are available in various VHH, Fab, and scFv formats. These libraries can be leveraged to develop monoclonal antibodies, bi- or multi-specifics, and chimeric antigen receptors (CARs) for CAR-T cell therapy.
A Proven Discovery Engine
Internal discovery efforts using the library of libraries have led to the generation and optimization of lead antibody agonists, antagonists, and binders, with robust pre-clinical data packages. Our fully-humanized antibodies and VHH nanobodies are available for licensing. They make it possible to drug high-value targets in broad therapeutic areas, including immuno-oncology, oncology, metabolic diseases, and more.
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Antibody enthusiasts are standing by and would love to hear more about your discovery needs. Challenging targets welcome!
