Documented transboundary transmission of mpox between the Central African Republic and the Democratic Republic of the Congo

medRxiv, Aug 2024

DOI: 10.1101/2024.08.13.24311555

Documented transboundary transmission of mpox between the Central African Republic and the Democratic Republic of the Congo

Hasivirwe Vakaniaki, Emmanuel ; Kinganda-Lusamaki, Eddy ; Merritt, Sydney ; Kasongo, Francois ; Malembi, Emile ; Lunyanga, Lygie ; Linsuke, Sylvie ; Halbrook, Megan ; Kalthan, Ernest ; Pukuta, Elisabeth ; Amuri Aziza, Adrienne ; Makangara Cigolo, Jean Claude ; Lumembe, Raphael ; Kabamba, Gabriel ; Anta, Yvon ; Bolunza, Pierrot ; Kanda, Innocent ; Nganzobo, Raoul ; Kalonji, Thierry ; Nsio, Justus ; Matoka, Patricia ; Mwamba, Dieudonné ; Ngandu, Christian ; Shaw, Souradet Y. ; Shongo, Robert ; Madinga, Joule ; Boum, Yap ; Liesenborghs, Laurens ; Delaporte, Eric ; Ayouba, Ahidjo ; Low, Nicola ; Ahuka Mundeke, Steve ; Hensley, Lisa E. ; Muyembe Tamfum, Jean-Jacques ; Nakoune, Emmanuel ; Peeters, Martine ; Hoff, Nicole A. ; Kindrachuk, Jason ; Rimoin, Anne W. ; Mbala-Kingebeni, Placide

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ABSTRACT

Four confirmed mpox cases in South Ubangi province, Democratic Republic of the Congo, were linked to documented transboundary transmission from Central African Republic. Viral genome sequencing shows that the MPXV sequences belong to subclade Ia. This demonstrates the borderless nature of mpox and highlights the need for vigilant regional surveillance.

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