我们的 DNA 中存在多样性

像您一样的人们正在创造未来。在 Twist,因为 Twist 人每天都在给他们的工作加入各种各样的经历和背景,这使得我们都变得更加强大。以下是 Twist 在全球的一些驻点,Twist 员工在这些地方不断成长。
团队地图

领导团队

  • Emily Leproust 博士——Twist Bioscience
    Emily Leproust 博士

    Twist 首席执行官兼联合创始人

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    Emily Leproust 博士——Twist Bioscience

    Emily Leproust 博士

    Twist 首席执行官兼联合创始人

    作为高通量合成和 DNA 测序的先驱者,Leproust 博士正在颠覆市场,以实现 DNA 应用的指数级增长,包括化学品/材料、诊断、治疗、食品和数字数据存储。2020 年,BIO 向她颁发了 Rosalind Franklin 领导奖。《外交政策》杂志将她评为 100 位全球领先思想家之一,而 Fast Company 则将她评为商界最具创造力的人物之一。加入 Twist Bioscience 之前,她曾在 Agilent Technologies 履任要职,期间曾设计出大获成功的 SureSelect 生产线,从而降低了测序成本,并阐明了数十种孟德尔疾病的机制。她还开发了寡核苷酸库合成技术,并启动和领导了团队的产品和业务拓展活动。Leproust 博士设计并开发了多个商业合成平台,用于简化微阵列芯片的生产制造过程。She serves on the Board of Directors of GeneDx and is a co-founder of Petri, an accelerator for start-ups at the forefront of engineering and biology. Leproust 博士发表过 30 多篇经过同行评议的论文,其中许多是关于合成 DNA 的应用,同时她还是多项专利的作者。她曾在休斯顿大学取得有机化学博士学位,并在里昂工业化学学院取得工业化学硕士学位。 

    出版物
    Structure-guided SCHEMA recombination generates diverse chimeric channelrhodopsins

    Bedbrook CN, Rice AJ, Yang KK, Ding X, Chen S, LeProust EM, Gradinaru V, Arnold FH.

    PNAS. 2017 114(13) E2624-E2633
    Polycomb repressive complex PRC1 spatially constrains the mouse embryonic stem cell genome

    Schoenfelder S, Sugar R, Dimond A, Javierre B, Armstrong H, Mifsud B, Dimitrova E, Matheson L, Tavares-Cadete F, Furlan-Magaril M, Segonds-Pichon A, Jurkowski W, Wingett SW, Tabbada K, Andrews S, Herman B, LeProust EM, Osborne CS, Koseki H, Fraser P, Luscombe NM, Elderkin S.

    Nature Genetics. 2015 47 1179–1186
    Mapping long-range promoter contacts in human cells with high-resolution capture Hi-C

    Mifsud B, Tavares-Cadete F, Young AN, Sugar R, Schoenfelder S, Ferreira L, Wingett SW, Andrews S, Grey W, Ewels PA, Herman B, Happe S, Higgs A, LeProust EM, Follows GA, Fraser P, Luscombe NM, Osborne CS.

    Nature Genetics. 47 (6) 598-606.
    The pluripotent regulatory circuitry connecting promoters to their long-range interacting elements

    Schoenfelder S, Furlan-Magaril M, Mifsud B, Tavares-Cadete F, Sugar, R, Javierre B, Nagano T, Katsman Y, Sakthidevi M, Wingett SW, Dimitrova E, Dimond A, Edelman LB, Elderkin S, Tabbada K, Darbo E, Andrews S, Herman B, Higgs A, LeProust EM, Osborne CS, Mitchell JA, Luscombe NM, Fraser P.

    Genome Res. 2015. 25: 582-597
    Utilizing ethnic-specific differences in minor allele frequency to recategorize reported pathogenic deafness variants

    Shearer AE, Eppsteiner RW, Booth KT, Ephraim SS, Gurrola J, Simpson A, Black-Ziegelbein EA, Joshi S, Ravi H, Giuffre AC, Happe S, Hildebrand MS, Azaiez H, Bayazit YA, Erdal ME, Lopez-Escamez JA, Gazquez I, Tamayo ML, Gelvez NY, Leal GL, Jalas C, Ekstein J, Yang T, Usami S, Kahrizi K, Bazazzadegan N, Najmabadi H, Scheetz TE, Braun TA, Casavant TL, LeProust EM, Smith RJ.

    The American Journal of Human Genetics. 95 4 445-453



    Systematic Identification of Barriers to Human iPSC Generation

    Qin H, Diaz A, Blouin L, Lebbink RJ, Patena W, Tanbun P, LeProust EM, McManus MT, Song JS, Ramalho-Santos M.

    158 (2) 449–461



    A high-coverage shRNA screen identifies TMEM129 as an E3 ligase involved in ER-associated protein degradation

    van de Weijer ML, Bassik MC, Luteijn RD, Voorburg CM, Lohuis MA, Kremmer E, Hoeben RC, LeProust EM, Chen S, Hoelen H, Ressing ME, Patena W, Weissman JS, McManus MTa, Wiertz, EJa, and Lebbink RJa.

    Nat Commun. (2014) 5: 3832.
    Evidence for the biogenesis of more than 1,000 novel human microRNAs

    Friedländer MR, Lizano E, Houben AJS, Bezdan D, Báñez-Coronel M, Kudla G, Mateu-Huertas E, Kagerbauer B, González J, Chen KC, LeProust EM, Martí E, Estivill X.

    Genome biology. 2014 15:R57
    Exonic Transcription Factor Binding Directs Codon Choice and Affects Protein Evolution

    Stergachis AB, Haugen E, Shafer A, Fu W, Vernot B, Reynolds A, Raubitschek A, Ziegler S, LeProust EM, Akey JM, Stamatoyannopoulos JA.

    Science. 2013 342(6164) 1367-1372
    Advancing genetic testing for deafness with genomic technology.

    Shearer AE, Black-Ziegelbein EA, Hildebrand MS, Eppsteiner RW, Ravi H, Joshi S, Guiffre AC, Sloan CM, Happe S, Howard SD, Novak B, Deluca AP, Taylor KR, Scheetz TE, Braun TA, Casavant TL, Kimberling WJ, Leproust EM, Smith RJ.

    Journal of Medical Genetics. 2013 50(9) 627-34
    A systematic mammalian genetic interaction map reveals pathways underlying ricin susceptibility.

    Bassik MC, Kampmann M, Lebbink RJ, Wang S, Hein MY, Poser I, Weibezahn J, Horlbeck MA, Chen S, Mann M, Hyman AA, Leproust EM, McManus MT, Weissman JS.

    Cell. 2013 152(4) 909-22
    Towards practical, high-capacity, low-maintenance information storage in synthesized DNA.

    Goldman N, Bertone P, Chen S, Dessimoz C, LeProust EM, Sipos B, Birney E.

    Nature. 2013 494(7435) 77-80
    Targeted genome enrichment for efficient purification of endosymbiont DNA from host DNA.

    Geniez S, Foster JM, Kumar S, Moumen B, Leproust E, Hardy O, Guadalupe M, Thomas SJ, Boone B, Hendrickson C, Bouchon D, Grève P, Slatko BE.

    Symbiosis. 2012 58 (1-3) 201-207
    Mitochondrial disease genetic diagnostics: optimized whole-exome analysis for all MitoCarta nuclear genes and the mitochondrial genome.

    Falk MJ, Pierce EA, Consugar M, Xie MH, Guadalupe M, Hardy O, Rappaport EF, Wallace DC,LeProust E, Gai X.

    Discovery Medicine. 2012 14(79) 389-99
    Pre-capture multiplexing improves efficiency and cost-effectiveness of targeted genomic enrichment.

    Shearer AE, Hildebrand MS, Ravi H, Joshi S, Guiffre AC, Novak B, Happe S, LeProust EM, Smith RJ. BMC Genomics. 2012 13 618
    Target enrichment strategies for next generation sequencing.

    Leproust E.

    Medical Laboratory Observer. 2012 44(6) 26-7
    Myofibrillar myopathy caused by a mutation in the motor domain of mouse MyHC IIb.

    Kurapati R, McKenna C, Lindqvist J, Williams D, Simon M, LeProust E, Baker J, Cheeseman M, Carroll N, Denny P, Laval S, Lochmüller H, Ochala J, Blanco G.

    Human Molecular Genetics. 2012 21(8) 1706-24
    Specific capture and whole-genome sequencing of viruses from clinical samples.

    Depledge DP, Palser AL, Watson SJ, Lai IY, Gray ER, Grant P, Kanda RK, Leproust E, Kellam P, Breuer J.

    PLoS One. 2011 6(11) e27805
    Autoantigen discovery with a synthetic human peptidome.

    Larman HB, Zhao Z, Laserson U, Li MZ, Ciccia A, Gakidis MA, Church GM, Kesari S, Leproust EM, Solimini NL, Elledge SJ.

    Nature Biotechnology. 2011 29(6) 535-41
    Efficient and cost effective population resequencing by pooling and in-solution hybridization.

    Bansal V, Tewhey R, Leproust EM, Schork NJ.

    PLoS One. 2011 6(3) e18353
    The GENCODE exome: sequencing the complete human exome.

    Coffey AJ, Kokocinski F, Calafato MS, Scott CE, Palta P, Drury E, Joyce CJ, Leproust EM, Harrow J, Hunt S, Lehesjoki AE, Turner DJ, Hubbard TJ, Palotie A.

    European Journal Human Genetics. 2011 19(7) 827-31
    Scalable gene synthesis by selective amplification of DNA pools from high-fidelity microchips.

    Kosuri S, Eroshenko N, Leproust EM, Super M, Way J, Li JB, Church GM.

    Nature Biotechnology. 2010 28(12) 1295-9
    Temporal and spatial profile of brain diffusion-weighted MRI after cardiac arrest.

    Mlynash M, Campbell DM, Leproust EM, Fischbein NJ, Bammer R, Eyngorn I, Hsia AW, Moseley M, Wijman CA.

    Stroke. 2010 41(8) 1665-72
    Synthesis of high-quality libraries of long (150mer) oligonucleotides by a novel depurination controlled process.

    LeProust EM, Peck BJ, Spirin K, McCuen HB, Moore B, Namsaraev E, Caruthers MH.

    Nucleic Acids Research. 2010 38(8) 2522-40
    Enrichment of sequencing targets from the human genome by solution hybridization.

    Tewhey R, Nakano M, Wang X, Pabón-Peña C, Novak B, Giuffre A, Lin E, Happe S, Roberts DN,LeProust EM, Topol EJ, Harismendy O, Frazer KA.

    Genome Biology. 2009 10(10) R116
    Digital RNA allelotyping reveals tissue-specific and allele-specific gene expression in human.

    Zhang K, Li JB, Gao Y, Egli D, Xie B, Deng J, Li Z, Lee JH, Aach J, Leproust EM, Eggan K, Church GM.

    Nature Methods. 2009 6(8) 613-8
    Multiplex padlock targeted sequencing reveals human hypermutable CpG variations.

    Li JB, Gao Y, Aach J, Zhang K, Kryukov GV, Xie B, Ahlford A, Yoon JK, Rosenbaum AM, Zaranek AW, LeProust E, Sunyaev SR, Church GM.

    Genome Research. 2009 19(9) 1606-15
    Genome-wide identification of human RNA editing sites by parallel DNA capturing and sequencing.

    Li JB, Levanon EY, Yoon JK, Aach J, Xie B, Leproust E, Zhang K, Gao Y, Church GM.

    Science. 2009 324(5931) 1210-3
    Rapid creation and quantitative monitoring of high coverage shRNA libraries.

    Bassik MC, Lebbink RJ, Churchman LS, Ingolia NT, Patena W, LeProust EM, Schuldiner M, Weissman JS, McManus MT.

    Nature Methods. 2009 6(6) 443-5
    Targeted bisulfite sequencing reveals changes in DNA methylation associated with nuclear reprogramming.

    Deng J, Shoemaker R, Xie B, Gore A, LeProust EM, Antosiewicz-Bourget J, Egli D, Maherali N, Park IH, Yu J, Daley GQ, Eggan K, Hochedlinger K, Thomson J, Wang W, Gao Y, Zhang K.

    Nature Biotechnology. 2009 27(4) 353-60
    Targeted and genome-scale strategies reveal gene-body methylation signatures in human cells.

    Ball MP, Li JB, Gao Y, Lee JH, LeProust EM, Park IH, Xie B, Daley GQ, Church GM.

    Nature Biotechnology. 2009 27(4) 361-8
    Solution hybrid selection with ultra-long oligonucleotides for massively parallel targeted sequencing.

    Gnirke A, Melnikov A, Maguire J, Rogov P, LeProust EM, Brockman W, Fennell T, Giannoukos G, Fisher S, Russ C, Gabriel S, Jaffe DB, Lander ES, Nusbaum C.

    Nature Biotechnology. 2009 27(2) 182-9
    The DNA-encoded nucleosome organization of a eukaryotic genome.

    Kaplan N, Moore IK, Fondufe-Mittendorf Y, Gossett AJ, Tillo D, Field Y, LeProust EM, Hughes TR, Lieb JD, Widom J, Segal E.

    Nature. 2009 458(7236) 362-6
    Multiplex amplification of large sets of human exons.

    Porreca GJ, Zhang K, Li JB, Xie B, Austin D, Vassallo SL, LeProust EM, Peck BJ, Emig CJ, Dahl F, Gao Y, Church GM, Shendure J.

    Nature Methods. 2007 4(11) 931-6
    Production of complex nucleic acid libraries using highly parallel in situ oligonucleotide synthesis.

    Cleary MA, Kilian K, Wang Y, Bradshaw J, Cavet G, Ge W, Kulkarni A, Paddison PJ, Chang K, Sheth N, Leproust E, Coffey EM, Burchard J, McCombie WR, Linsley P, Hannon GJ.

    Nature Methods. 2004 1(3) 241-8
    Effects of atmospheric ozone on microarray data quality.

    Fare TL, Coffey EM, Dai H, He YD, Kessler DA, Kilian KA, Koch JE, LeProust E, Marton MJ, Meyer MR, Stoughton RB, Tokiwa GY, Wang Y.

    Analytical Chemistry. 2003 75(17) 4672-5
    A flexible light-directed DNA chip synthesis gated by deprotection using solution photogenerated acids.

    Gao X, LeProust E, Zhang H, Srivannavit O, Gulari E, Yu P, Nishiguchi C, Xiang Q, Zhou X.

    Nucleic Acids Research. 2001 29(22) 4744-50.
    Characterization of oligodeoxyribonucleotide synthesis on glass plates.

    LeProust E, Zhang H, Yu P, Zhou X, Gao X.

    Nucleic Acids Research. 2001 29(10) 2171-80
    Unexpected formation of parallel duplex in GAA and TTC trinucleotide repeats of Friedreich's ataxia.

    LeProust EM, Pearson CE, Sinden RR, Gao X.

    Journal of Molecular Biology. 2000 302(5) 1063-80
    Digital light-directed synthesis. A microarray platform that permits rapid reaction optimization on a combinatorial basis.

    LeProust E, Pellois JP, Yu P, Zhang H, Gao X, Srivannavit O, Gulari E, Zhou X.

    Journal of Combinatorial Chemistry. 2000 2(4) 349-54
  • Patrick Finn

    President and Chief Operating Officer

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    Patrick Finn

    President and Chief Operating Officer

    Patrick 此前在生物试剂、B2B 和定制制造企业有着良好表现,成功实现了销售额的高速增长。他拥有相关的技术背景,并且能够识别出客户未被满足的需求,因此适合领导我们的商务工作。Paddy 在加入 Twist Bioscience 之前任职于 Enzymatics(近期被 QIAGEN 收购),担任销售与市场副总裁,负责领导北美和欧洲的商务活动;他在任职期间实现了显著的顶线增长,并将业务范围延伸到了商务客户。加入 Enzymatics 之前,Paddy 曾任多个商务要职,包括 Agilent Technologies 的业务开发总监、Beckman Coulter Molecular Diagnostics 的产品开发总监以及 Invitrogen and GE Healthcare/Amersham International 产品开发部门的多个技术职位。此外,Paddy 博士目前还任职于 Lasergen 的科学顾问委员会,并且之前曾任职于 Enzymatics 的科学顾问委员会。他拥有南安普敦大学的核酸化学博士学位和赫瑞瓦特大学荣誉商学士学位。

  • Adam Laponis

    首席财务官

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    Adam Laponis

    首席财务官

    Adam has deep financial acumen and strategic planning expertise across diverse businesses along with a track record of collaborating across teams to drive profitable growth. Prior to joining Twist, Adam served as chief financial officer of Eargo, Inc., where he was responsible for finance, accounting, investor relations, business operations, internal audit and information technology. During his tenure at Eargo, revenue increased more than 300% over the course of two years. Prior to Eargo, Adam was vice president, worldwide financial planning and analysis and business operations at Tesla, Inc. where he was responsible for worldwide pricing, forecasting, capital planning, development of internal controls, and optimization of business operations. Previously, Adam served as vice president, finance and chief financial officer, cardiovascular care at Cardinal Health as the finance leader for the worldwide Cordis Cardiovascular business. He held a series of roles of increasing responsibility at Johnson & Johnson, where he led the divestiture of Cordis to Cardinal Health. He held additional positions within Johnson & Johnson including controller of the diabetes franchise, manager of supply chain and quality finance and customer service finance. Adam holds an MBA from the University of Southern California, Marshall School of Business and a B.S. in chemical engineering from the University of California at Berkeley.

  • Nicole Moreno
    Nicole Moreno

    Senior Vice President of Sales and Support

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    Nicole Moreno

    Nicole Moreno

    Senior Vice President of Sales and Support

    Nicole is a visionary sales leader with over 17 years of experience driving commercial success within NGS, synthetic biology, molecular diagnostics and RNA therapeutics. She has a proven track record of building and coaching high-performing sales teams at local, national and global levels, and implementing innovative sales methodologies to meet evolving customer needs. Since joining Twist in 2020, Nicole has consistently delivered high growth sales across various vertical markets, serving in escalating positions within the commercial team. She was appointed SVP of Sales and Support in October 2024.

    Before Twist Bioscience, Nicole held multiple leadership roles within the North America Custom Solutions & OEM sales teams at QIAGEN. During her tenure at QIAGEN, she successfully led the North American sales teams to achieve more than double team sales in 3 years and was recognized as a QIAGEN President's Circle Award Winner. Previously, Nicole served in senior sales roles at Enzymatics (a QIAGEN company), where she expanded the Western Region by driving customer and revenue growth through new business opportunities. Prior to Enzymatics, Nicole held positions at Affymetrix and USB Corporation where she substantially increased revenue growth through strategic account management and business development.

    Nicole holds a B.S. in Biochemistry from Colorado State University.

  • 陈思远
    陈思远

    首席技术官

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    陈思远

    陈思远

    首席技术官

    陈博士是一位战略思想家,他在识别、开发和发布 NGS、合成生物学和其他生命科学领域的创新产品方面有着丰富经验。Twist 成立后不久,他就加入了公司,主要负责合成生物学和 NGS 产品系列的开发。陈博士构思并实施了包含对 SARS-CoV-2 和其他传染病的合成控制在内的全新 NGS 产品线,开发了基因合成和 NGS 靶向富集生物化学、工作流、试剂盒和基础设施,并联合硬件、软件和硅等领域的工程师们共同构建了公司的原型 DNA 合成器,为 Twist 奠定了技术基础,实现了规模化生产。陈博士发表了众多经过同行评议的论文,并在寡核苷酸合成和合成寡核苷酸的应用领域拥有多项专利。他在威斯康星大学麦迪逊分校获得了化学博士学位,在中国北京大学获得了化学学士学位。 

  • Paula Green

    人力资源高级副总裁

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    Paula Green

    人力资源高级副总裁

    Paula Green 是一位经验丰富的人力资源执行官,他在开发和使用有关提升领导力、赋能高效组织的高影响力人员战略、解决方案、流程和工具方面有着骄人业绩。加入 Twist Bioscience 之前,她曾担任 QIAGEN 公司的人力资源副总裁,并在并购重组和其他重大的企业交易中负责带领 50 名人力资源专家,为 4,000 名员工提供支持。她曾是 Operon Technologies(被 QIAGEN 收购)的人力资源经理,主要负责制定战略、监督所有员工的福利以及提供培训、招聘和留用项目。她还曾担任旧金山联邦住房贷款银行的人力资源顾问。Paula 拥有旧金山大学的组织行为学学士学位。 

  • Mike Fero
    Mike Fero

    Chief Information Officer

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    Mike Fero

    Mike Fero

    Chief Information Officer

    Mike is a seasoned executive with experience leading startups, developing commercial software, researching biology and physics and working in fast-paced deep-tech businesses.

    Before joining Twist, he co-founded and served as CEO of TeselaGen Biotechnology for a decade, where he spearheaded TeselaGen’s enterprise software platform, providing a comprehensive suite of tools for DNA design, assembly, management and experimental workflows to a range of biotech customers from startups to Fortune 50 companies. Prior to TeselaGen, he was a principal investigator and NIH Career Fellow at Stanford University where he explored the signaling pathways that govern the bacteria cell cycle through the development of an automated epifluorescence microscopy platform including both hardware and software for high-throughput, high-content genetic screens and subsequent data analysis. He also served as director of Stanford Functional Genomics, where he collaborated on the development of the first human and murine genome scale microarrays. Prior to Stanford, Mike served as vice president of software engineering at Neomorphic where he guided development of a laboratory information management system (LIMS) solution for the human genome project at Lawrence Berkeley National Laboratory. Before Neomorphic, he held a variety of escalating positions at HyperParallel and Massachusetts Institute of Technology. 

    Mike holds a Ph.D. in Physics and a B. A. in both Math and Physics, both from the University of California, Irvine. He completed a postdoctoral fellowship at the Massachusetts Institute of Technology, Cambridge and conducted international studies in Maths at Trinity College, Dublin. He serves as an advisor to both government and private groups exploring the promise, limits and concerns around the field of synthetic biology.

    出版物
    • Fero MJ, Craft JK, Vu T, Hillson NJ. Combinatorial-Hierarchical DNA Library Design Using the TeselaGen DESIGN Module with j5. Methods Mol Biol. 2020;2205:19-47.
    • Zhang J, Petersen SD, Radivojevic T, Ramirez A, Pérez-Manríquez A, Abeliuk E, Sánchez BJ, Costello Z, Chen Y, Fero MJ, Martin HG, Nielsen J, Keasling JD, Jensen MK. Combining mechanistic and machine learning models for predictive engineering and optimization of tryptophan metabolism. Nat Commun. 2020 9 月 25 日;11(1):4880.
    • “HEEBO and MEEBO Chips – Human and Mouse Exonic Evidence-Based Oligonucleotide Reporters for Microarray Based Expression Analysis,” Keystone Symposia Conference, Systems Biology: Integrating Biology, Technology and Computation, 2006 年 3 月 5 日.
    • Plahar HA, Rich TN, Lane SD, Morrell WC, Springthorpe L, Nnadi O, Aravina E, Dai T, Fero MJ, Hillson NJ, Petzold CJ. BioParts-A Biological Parts Search Portal and Updates to the ICE Parts Registry Software Platform. ACS Synth Biol. 2021 10 月 15 日;10(10):2649-2660.
    • Goyal G, Elsbree N, Fero M, Hillson NJ, Linshiz G. Repurposing a microfluidic formulation device for automated DNA construction. PLoS One. 2020 11 月 11 日;15(11):e0242157.
    • Cable J, Leonard JN, Lu TK, Xie Z, Chang MW, Fernández LÁ, Lora JM, Kaufman HL, Quintana FJ, Geiger R, F Lesser C, Lynch JP, Hava DL, Cornish VW, Lee GK, DiAndreth B, Fero M, Srivastava R, De Coster T, Roybal KT, Rackham OJL, Kiani S, Zhu I, Hernandez-Lopez RA, Guo T, Chen WCW. Synthetic biology: at the crossroads of genetic engineering and human therapeutics-a Keystone Symposia report. Ann N Y Acad Sci. 2021 Dec;1506(1):98-117.
    • Hodgson, A., Alper, J., Maxon, M.E. 2022. The U.S. Bioeconomy: Charting a Course for a Resilient and Competitive Future. New York, New York: Schmidt Futures. doi.org/10.55879/d2hrs7zwc.
    • Eichenbaum, A., Miłowski, A., Beverly, A., Fero, M., Downs, M., Treynor, T., Gibbons, S., Venayak, N., Densmore, D., Provencher, L., Veeramalla, R., Yan, H., Lee, H., Stamps, B., Dobbs, T., Cheng, M., Dunlap, C., Ly, K., Saryan, L. 2024. Data Modeling and Coding Standards. BioMADE Digital Infrastructure Committee (unpublished).
    • B Christen,* MJ Fero,* NJ Hillson, G Bowman, S-H Hong, L Shapiro, HH McAdams: High throughput identification of protein localization dependency networks. Proceedings of the National Academy of Sciences USA 2010, 107(10):4681-4686. *equal contribution.
    • Fero M, Pogliano K. Automated quantitative live cell fluorescence microscopy. Cold Spring Harbor perspectives in biology. 2010 8 月 1 日;2(8):a000455.
    • Fero M, Christen B, Hillson N, Bowman G, Hong S, Shapiro L, McAdams H. Illuminating complete functional networks: Automation, computation and the single cell F1000research. 1. doi: 10.7490/F1000Research.367.1 
    • Christen B, Abeliuk E, Collier JM, Kalogeraki V, Passarelli B, Coller JA, Fero MJ, McAdams HH, Shapiro L: The Essential Genome of a Bacterium, Molecular Systems Biology 2011, 7(528).
    • Umbarger MA, Toro E, Wright MA, Porreca GJ, Baù D, Hong SH, Fero MJ, Zhu LJ, Marti-Renom MA, McAdams HH, Shapiro L, Dekker J, Church GM. The three-dimensional architecture of a bacterial genome and its alteration by genetic perturbation. Mol Cell. 2011 10 月 21 日;44(2):252-64.
    • K Abe, et al: An improved measurement of the left-right Z0 cross-section asymmetry. Physical Review Letters 1997, 78:2075-2079.
  • Mark Buck

    Senior Vice President of Operations

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    Mark Buck

    Senior Vice President of Operations

    Mark is experienced in improving manufacturing efficiency and driving revenue and margin through managing supply chain and operations, including planning, quality, procurement and logistics. Prior to joining Twist, Mark served as corporate senior vice president, operations, global supply chain at Excelitas Technologies Corporation where he established a global footprint, drove global supply chain optimization measures, enabled scale up and drove revenue growth. His responsibilities included global supply chain planning, global sourcing and procurement supply, internal supply, supply quality and logistics inbound and outbound movement of freight. Prior to Excelitas, Mark was director, global supply chain management and general manager of resale product operations at Bio-Rad, Inc., where he managed buy-sell products, which grew in revenue to $270 million, significantly improving profitability over his time in the role. He previously held leadership positions including vice president operations, global manufacturing, supply chain and logistics at Celerity Group; director, operations management at Solectron corporation; and senior supply chain operations manager at Apple Computer, Inc. Before joining industry, Mark served in the United States Marine Corps. He holds an MBA from National University and a B.S. in electrical and computer engineering from University of Illinois, Urbana-Champaign.

  • Bill Banyai 博士

    先进技术开发高级副总裁兼数据存储总经理

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    Bill Banyai 博士

    先进技术开发高级副总裁兼数据存储总经理

    Bill 是一位经验丰富的企业家和硅工程专家。他曾是四家初创企业的创始人或首位员工,并为初创企业提供咨询。作为 Complete Genomics 的硬件工程副总裁,他主导建立了自己的测序技术,并交付了三代人类基因组芯片和测序仪。Bill 曾两次获得美国国防部高级研究计划局 (DARPA) 的数百万美元拨款,用于开发基于硅微机械加工的创新技术。Bill 的职业生涯横跨了研究、产品开发和半导体器件加工等领域。他拥有亚利桑那大学的光学科学博士学位和密歇根大学的电子科学硕士学位,并曾在劳伦斯利弗莫尔国家实验室担任物理学家。

    出版物
    Human Genome Sequencing Using Unchained Base Reads on Self-Assembling DNA Nanoarrays.

    Drmanac R, Sparks AB, Callow MJ, Halpern AL, Burns NL, Kermani BG, Carnevali P, Nazarenko I, Nilsen GB, Yeung G, Dahl F, Fernandez A, Staker B, Pant KP, Baccash J, Borcherding AP, Brownley A, Cedeno R, Chen L, Chernikoff D, Cheung A, Chirita R, Curson B, Ebert JC, Hacker CR, Hartlage R, Hauser B, Huang S, Jiang Y, Karpinchyk V, Koenig M, Kong C, Landers T, Le C, Liu J, McBride CE, Morenzoni M, Morey RE, Mutch K, Perazich H, Perry K, Peters BA, Peterson J, Pethiyagoda CL, Pothuraju K, Richter C, Rosenbaum AM, Roy S, Shafto J, Sharanhovich U, Shannon KW, Sheppy CG, Sun M, Thakuria JV, Tran A, Vu D, Zaranek AW, Wu X, Drmanac S, Oliphant AR, Banyai WC, Martin B, Ballinger DG, Church GM, Reid CA.

    Science. 2010 327(5961) 78-81
    Modular MEMS design and fabrication for an 80 x 80 transparent optical cross-connect switch.

    Fernandez A, Staker BP, Owens WE, Muray LP, Spallas JP, Banyai WC.

    Proceedings SPIE - Optomechatronic Micro/Nano Components, Devices, and Systems. 2004 5604 208-217
    Scaling behavior in interference lithography.

    Agayan RR, Banyai WC, Fernandez AJ.

    Proceedings SPIE - Emerging Lithographic Technologies II. 1998 3331 662-672
    Time-to-frequency converter for measuring picosecond optical pulses.

    Kauffman MT, Banyai WC, Godil AA, Bloom DM.

    Applied Physics Letters. 1994 64(3) 270-272
    Applications of time lens optical systems.

    Kauffman MT, Godil AA, Auld BA, Banyai WC, Bloom DM.

    Electronics Letters. 1993 29(3) 268-269
    Interaction of super-intense light fields with atoms and surfaces.

    Downer MC, Banyai WC, Wood WM, Anacker DC, Erskine JL.

    Proceedings SPIE - Picosecond and Femtosecond Spectroscopy from Laboratory to Real World. 1990 1209 166-174
    Spectral shifting of femtosecond pulses in atmospheric density plasmas.

    Spectral shifting of femtosecond pulses in atmospheric density plasmas.

     
    Picosecond pump-probe interferometric measurement of optical nonlinearities in channel waveguides.

    Finlayson N, Banyai WC, Seaton CT, Stegeman GI, O'Neill M, Cullen TJ, Ironside CN.

    Optics Letters. 1989 14(10) 532-534
    Optical nonlinearities in CdSxSe1-x-doped glass waveguides.

    Finlayson N, Banyai WC, Seaton CT, Stegeman GI, O'Neill M, Cullen TJ, Ironside CN.

    Journal of the Optical Society of America B: Optical Physics. 1989 6(4) 675-684
    Saturation of the nonlinear refractive-index change in a semiconductor-doped glass channel waveguide.

    Banyai WC, Finlayson N, Seaton CT, Stegeman GI, O’Neill M, Cullen TJ, Ironside CN.

    Applied Physics Letters. 1989 54(6) 481-483
    Observation of ultrafast nonlinear polarization switching induced by polarization instability in a birefringent fiber rocking filter.

    Trillo S, Wabnitz S, Banyai WC, Finlayson N, Seaton CT, Stegeman GI, Stolen RH.

    IEEE Journal of Quantum Electronics. 1989 25(1) 104-112
    Picosecond switching induced by saturable absorption in a nonlinear directional coupler.

    Finlayson N, Banyai WC, Wright EM, Seaton CT., Stegeman GI, Cullen TJ, Ironside CN.

    Applied Physics Letters. 1988 53(13) 1144-1146
    Picosecond nonlinear polarization switching with a fiber filter.

    Trillo S, Wabnitz S, Finlayson N, Banyai WC, Seaton CT, Stegeman GI, Stolen RH.

    Applied Physics Letters. 1988 53(10) 837-839
    Nonlinear-optical effects in ion-exchanged semiconductor-doped glass waveguides.

    Ironside CN, Cullen TJ, Bhumbra BS, Bell JA, Banyai WC, Finlayson N, Seaton CT, Stegeman GI.

    Journal of the Optical Society of America B: Optical Physics. 1988 5(2) 492-495
    High-speed intensity-dependent refractive index in semiconductor-doped glasses.

    Seaton CT, Stegeman GI, Yao SS, Karaguleff C, Fortenberry R, Gabel A, Banyai W, Assanto G.

    Proceedings SPIE - Advances in Materials for Active Optics. 1985 567 132
  • 首席 ESG 官兼公司事务高级副总裁
    Angela Bitting

    首席 ESG 官兼公司事务高级副总裁

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    首席 ESG 官兼公司事务高级副总裁

    Angela Bitting

    首席 ESG 官兼公司事务高级副总裁

    作为一名在生物制药行业拥有超过 25 年经验的高级传播主管,Angela 擅于清晰的表达和一致的传播,这让她在主要利益相关者中获得了一定的知名度,并承担了整个公司的文化和传播方面的工作。在加入 Twist 之前,她有 20 年的咨询服务经验,与生物制药、医疗设备和诊断领域的客户合作创建了关键信息,从而实现与外部受众的有效沟通。在开始咨询服务之前,Angela 曾担任 Exelixis 公司的投资者关系和企业传播部主管。她也在 Russell-Welsh 公司(一家精品医疗通信公司)工作了数年,期间与各种公共和私人客户就广泛的通信服务进行过合作。她拥有华盛顿大学的细胞和分子生物学理学学士学位和商业营销文学学士学位。她目前担任国家慈善联盟当地分会的临时副总裁。

  • Dennis Cho

    Chief Legal Officer and Corporate Secretary

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    Dennis Cho

    Chief Legal Officer and Corporate Secretary

    Dennis Cho is a seasoned in-house business attorney with a proven track record of agile strategic guidance and practical problem solving. Prior to Twist, he served as assistant general counsel at CytomX Therapeutics, where he was department head for all deals and contracts as well as day-to-day lead on compliance and numerous other legal subject matters. Prior to CytomX, Mr. Cho was the lead transactional attorney on antibody-related licenses and collaborations, major commercial agreements, and combination trials at Seattle Genetics. Before that, he spent nine years at Celgene as the lead West Coast attorney supervising over 100 business transactions, including in- and out- licenses, options, collaborations and M&A agreements, and held primary legal responsibility for Celgene’s alliances, equity investments and “big data” machine learning initiative. Prior to Celgene, Mr. Cho served as general counsel for four private and public companies. He earned his J.D. and a B.A. in Molecular Cell Biology (Genetics) from University of California, Berkeley.

团队介绍

董事会

Rob Chess

董事会主席
Nektar Therapeutics

Nelson C. Chan

董事会主席
Synaptics 和 Adesto

Keith Crandell

联合创始人兼总经理
Arch Venture Partners

Jan Johannessen

iGlobe Partners 顾问

Xiaoying Mai

Head of Private Equity, GF Investments (Hong Kong) Company Limited

Bob Ragusa

CEO
GRAIL, LLC

Melissa Starovasnik, Ph.D.

Former Vice President, Protein Sciences and Head of Large Molecule Drug Discovery
Genentech

Emily Leproust

首席执行官
Twist Bioscience

尽显才能,发光发热。

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