La diversité est dans notre ADN

L’avenir est façonné par des personnes telles que vous. Twist est plus forte grâce aux divers antécédents et expériences que ses employés exploitent tous les jours dans leur travail. Certains des lieux où les employés de Twist ont grandi sont indiqués ci-après.
Origine géographique des membres de l’équipe

Équipe dirigeante

  • Emily Leproust, PhD, Twist Bioscience
    Emily Leproust, PhD

    PDG et cofondatrice de Twist

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    Emily Leproust, PhD, Twist Bioscience

    Emily Leproust, PhD

    PDG et cofondatrice de Twist

    Pionnière de longue date dans le domaine de la synthèse et du séquençage de l’ADN à haut débit, le Dr Leproust bouleverse le marché pour permettre la croissance exponentielle d’applications relatives à l’ADN dans des secteurs tels que les produits/matériaux chimiques, les diagnostics, les traitements, l’alimentation et le stockage de données numériques. En 2020, BIO lui a décerné le trophée Rosalind Franklin Award for Leadership. Foreign Policy l’a citée comme l’un de ses 100 penseurs de pointe dans le monde (100 Leading Global Thinkers) et Fast Company comme l’une des personnes les plus créatives dans le secteur (Most Creative People in Business). Avant de travailler chez Twist Bioscience, elle a occupé des postes aux responsabilités croissantes chez Agilent Technologies où elle a façonné la gamme de produits SureSelect. Cette gamme, qui a connu un grand succès, a permis de réduire le coût du séquençage et a découvert les mécanismes responsables de dizaines de maladies mendéliennes. Elle a également développé la technologie Oligo Library Synthesis. Dans le cadre de ce travail, elle a lancé et dirigé le développement de produits et de l’activité pour l’équipe. Le Dr Leproust a conçu et développé plusieurs plateformes de synthèse commerciales afin de rationaliser la production et la fabrication de microréseaux. She serves on the Board of Directors of GeneDx and is a co-founder of Petri, an accelerator for start-ups at the forefront of engineering and biology. Le Dr Leproust a publié plus de 30 articles évalués par des pairs sur les nombreuses applications de l’ADN synthétique. Elle est également l’auteur de nombreux brevets. Elle a obtenu son doctorat (Ph.D) en chimie organique à l’Université de Houston et sa maîtrise ès sciences (M. Sc.) en chimie industrielle à la Lyon School of Industrial Chemistry. 

    Publications
    Structure-guided SCHEMA recombination generates diverse chimeric channelrhodopsins

    Bedbrook CN, Rice AJ, Yang KK, Ding X, Chen S, LeProust EM, Gradinaru V, Arnold FH.

    PNAS. 2017 114(13) E2624-E2633
    Polycomb repressive complex PRC1 spatially constrains the mouse embryonic stem cell genome

    Schoenfelder S, Sugar R, Dimond A, Javierre B, Armstrong H, Mifsud B, Dimitrova E, Matheson L, Tavares-Cadete F, Furlan-Magaril M, Segonds-Pichon A, Jurkowski W, Wingett SW, Tabbada K, Andrews S, Herman B, LeProust EM, Osborne CS, Koseki H, Fraser P, Luscombe NM, Elderkin S.

    Nature Genetics. 2015 47 1179–1186
    Mapping long-range promoter contacts in human cells with high-resolution capture Hi-C

    Mifsud B, Tavares-Cadete F, Young AN, Sugar R, Schoenfelder S, Ferreira L, Wingett SW, Andrews S, Grey W, Ewels PA, Herman B, Happe S, Higgs A, LeProust EM, Follows GA, Fraser P, Luscombe NM, Osborne CS.

    Nature Genetics. 47 (6) 598-606.
    The pluripotent regulatory circuitry connecting promoters to their long-range interacting elements

    Schoenfelder S, Furlan-Magaril M, Mifsud B, Tavares-Cadete F, Sugar, R, Javierre B, Nagano T, Katsman Y, Sakthidevi M, Wingett SW, Dimitrova E, Dimond A, Edelman LB, Elderkin S, Tabbada K, Darbo E, Andrews S, Herman B, Higgs A, LeProust EM, Osborne CS, Mitchell JA, Luscombe NM, Fraser P.

    Genome Res. 2015. 25: 582-597
    Utilizing ethnic-specific differences in minor allele frequency to recategorize reported pathogenic deafness variants

    Shearer AE, Eppsteiner RW, Booth KT, Ephraim SS, Gurrola J, Simpson A, Black-Ziegelbein EA, Joshi S, Ravi H, Giuffre AC, Happe S, Hildebrand MS, Azaiez H, Bayazit YA, Erdal ME, Lopez-Escamez JA, Gazquez I, Tamayo ML, Gelvez NY, Leal GL, Jalas C, Ekstein J, Yang T, Usami S, Kahrizi K, Bazazzadegan N, Najmabadi H, Scheetz TE, Braun TA, Casavant TL, LeProust EM, Smith RJ.

    The American Journal of Human Genetics. 95 4 445-453



    Systematic Identification of Barriers to Human iPSC Generation

    Qin H, Diaz A, Blouin L, Lebbink RJ, Patena W, Tanbun P, LeProust EM, McManus MT, Song JS, Ramalho-Santos M.

    158 (2) 449–461



    A high-coverage shRNA screen identifies TMEM129 as an E3 ligase involved in ER-associated protein degradation

    van de Weijer ML, Bassik MC, Luteijn RD, Voorburg CM, Lohuis MA, Kremmer E, Hoeben RC, LeProust EM, Chen S, Hoelen H, Ressing ME, Patena W, Weissman JS, McManus MTa, Wiertz, EJa, and Lebbink RJa.

    Nat Commun. (2014) 5: 3832.
    Evidence for the biogenesis of more than 1,000 novel human microRNAs

    Friedländer MR, Lizano E, Houben AJS, Bezdan D, Báñez-Coronel M, Kudla G, Mateu-Huertas E, Kagerbauer B, González J, Chen KC, LeProust EM, Martí E, Estivill X.

    Genome biology. 2014 15:R57
    Exonic Transcription Factor Binding Directs Codon Choice and Affects Protein Evolution

    Stergachis AB, Haugen E, Shafer A, Fu W, Vernot B, Reynolds A, Raubitschek A, Ziegler S, LeProust EM, Akey JM, Stamatoyannopoulos JA.

    Science. 2013 342(6164) 1367-1372
    Advancing genetic testing for deafness with genomic technology.

    Shearer AE, Black-Ziegelbein EA, Hildebrand MS, Eppsteiner RW, Ravi H, Joshi S, Guiffre AC, Sloan CM, Happe S, Howard SD, Novak B, Deluca AP, Taylor KR, Scheetz TE, Braun TA, Casavant TL, Kimberling WJ, Leproust EM, Smith RJ.

    Journal of Medical Genetics. 2013 50(9) 627-34
    A systematic mammalian genetic interaction map reveals pathways underlying ricin susceptibility.

    Bassik MC, Kampmann M, Lebbink RJ, Wang S, Hein MY, Poser I, Weibezahn J, Horlbeck MA, Chen S, Mann M, Hyman AA, Leproust EM, McManus MT, Weissman JS.

    Cell. 2013 152(4) 909-22
    Towards practical, high-capacity, low-maintenance information storage in synthesized DNA.

    Goldman N, Bertone P, Chen S, Dessimoz C, LeProust EM, Sipos B, Birney E.

    Nature. 2013 494(7435) 77-80
    Targeted genome enrichment for efficient purification of endosymbiont DNA from host DNA.

    Geniez S, Foster JM, Kumar S, Moumen B, Leproust E, Hardy O, Guadalupe M, Thomas SJ, Boone B, Hendrickson C, Bouchon D, Grève P, Slatko BE.

    Symbiosis. 2012 58 (1-3) 201-207
    Mitochondrial disease genetic diagnostics: optimized whole-exome analysis for all MitoCarta nuclear genes and the mitochondrial genome.

    Falk MJ, Pierce EA, Consugar M, Xie MH, Guadalupe M, Hardy O, Rappaport EF, Wallace DC,LeProust E, Gai X.

    Discovery Medicine. 2012 14(79) 389-99
    Pre-capture multiplexing improves efficiency and cost-effectiveness of targeted genomic enrichment.

    Shearer AE, Hildebrand MS, Ravi H, Joshi S, Guiffre AC, Novak B, Happe S, LeProust EM, Smith RJ. BMC Genomics. 2012 13 618
    Target enrichment strategies for next generation sequencing.

    Leproust E.

    Medical Laboratory Observer. 2012 44(6) 26-7
    Myofibrillar myopathy caused by a mutation in the motor domain of mouse MyHC IIb.

    Kurapati R, McKenna C, Lindqvist J, Williams D, Simon M, LeProust E, Baker J, Cheeseman M, Carroll N, Denny P, Laval S, Lochmüller H, Ochala J, Blanco G.

    Human Molecular Genetics. 2012 21(8) 1706-24
    Specific capture and whole-genome sequencing of viruses from clinical samples.

    Depledge DP, Palser AL, Watson SJ, Lai IY, Gray ER, Grant P, Kanda RK, Leproust E, Kellam P, Breuer J.

    PLoS One. 2011 6(11) e27805
    Autoantigen discovery with a synthetic human peptidome.

    Larman HB, Zhao Z, Laserson U, Li MZ, Ciccia A, Gakidis MA, Church GM, Kesari S, Leproust EM, Solimini NL, Elledge SJ.

    Nature Biotechnology. 2011 29(6) 535-41
    Efficient and cost effective population resequencing by pooling and in-solution hybridization.

    Bansal V, Tewhey R, Leproust EM, Schork NJ.

    PLoS One. 2011 6(3) e18353
    The GENCODE exome: sequencing the complete human exome.

    Coffey AJ, Kokocinski F, Calafato MS, Scott CE, Palta P, Drury E, Joyce CJ, Leproust EM, Harrow J, Hunt S, Lehesjoki AE, Turner DJ, Hubbard TJ, Palotie A.

    European Journal Human Genetics. 2011 19(7) 827-31
    Scalable gene synthesis by selective amplification of DNA pools from high-fidelity microchips.

    Kosuri S, Eroshenko N, Leproust EM, Super M, Way J, Li JB, Church GM.

    Nature Biotechnology. 2010 28(12) 1295-9
    Temporal and spatial profile of brain diffusion-weighted MRI after cardiac arrest.

    Mlynash M, Campbell DM, Leproust EM, Fischbein NJ, Bammer R, Eyngorn I, Hsia AW, Moseley M, Wijman CA.

    Stroke. 2010 41(8) 1665-72
    Synthesis of high-quality libraries of long (150mer) oligonucleotides by a novel depurination controlled process.

    LeProust EM, Peck BJ, Spirin K, McCuen HB, Moore B, Namsaraev E, Caruthers MH.

    Nucleic Acids Research. 2010 38(8) 2522-40
    Enrichment of sequencing targets from the human genome by solution hybridization.

    Tewhey R, Nakano M, Wang X, Pabón-Peña C, Novak B, Giuffre A, Lin E, Happe S, Roberts DN,LeProust EM, Topol EJ, Harismendy O, Frazer KA.

    Genome Biology. 2009 10(10) R116
    Digital RNA allelotyping reveals tissue-specific and allele-specific gene expression in human.

    Zhang K, Li JB, Gao Y, Egli D, Xie B, Deng J, Li Z, Lee JH, Aach J, Leproust EM, Eggan K, Church GM.

    Nature Methods. 2009 6(8) 613-8
    Multiplex padlock targeted sequencing reveals human hypermutable CpG variations.

    Li JB, Gao Y, Aach J, Zhang K, Kryukov GV, Xie B, Ahlford A, Yoon JK, Rosenbaum AM, Zaranek AW, LeProust E, Sunyaev SR, Church GM.

    Genome Research. 2009 19(9) 1606-15
    Genome-wide identification of human RNA editing sites by parallel DNA capturing and sequencing.

    Li JB, Levanon EY, Yoon JK, Aach J, Xie B, Leproust E, Zhang K, Gao Y, Church GM.

    Science. 2009 324(5931) 1210-3
    Rapid creation and quantitative monitoring of high coverage shRNA libraries.

    Bassik MC, Lebbink RJ, Churchman LS, Ingolia NT, Patena W, LeProust EM, Schuldiner M, Weissman JS, McManus MT.

    Nature Methods. 2009 6(6) 443-5
    Targeted bisulfite sequencing reveals changes in DNA methylation associated with nuclear reprogramming.

    Deng J, Shoemaker R, Xie B, Gore A, LeProust EM, Antosiewicz-Bourget J, Egli D, Maherali N, Park IH, Yu J, Daley GQ, Eggan K, Hochedlinger K, Thomson J, Wang W, Gao Y, Zhang K.

    Nature Biotechnology. 2009 27(4) 353-60
    Targeted and genome-scale strategies reveal gene-body methylation signatures in human cells.

    Ball MP, Li JB, Gao Y, Lee JH, LeProust EM, Park IH, Xie B, Daley GQ, Church GM.

    Nature Biotechnology. 2009 27(4) 361-8
    Solution hybrid selection with ultra-long oligonucleotides for massively parallel targeted sequencing.

    Gnirke A, Melnikov A, Maguire J, Rogov P, LeProust EM, Brockman W, Fennell T, Giannoukos G, Fisher S, Russ C, Gabriel S, Jaffe DB, Lander ES, Nusbaum C.

    Nature Biotechnology. 2009 27(2) 182-9
    The DNA-encoded nucleosome organization of a eukaryotic genome.

    Kaplan N, Moore IK, Fondufe-Mittendorf Y, Gossett AJ, Tillo D, Field Y, LeProust EM, Hughes TR, Lieb JD, Widom J, Segal E.

    Nature. 2009 458(7236) 362-6
    Multiplex amplification of large sets of human exons.

    Porreca GJ, Zhang K, Li JB, Xie B, Austin D, Vassallo SL, LeProust EM, Peck BJ, Emig CJ, Dahl F, Gao Y, Church GM, Shendure J.

    Nature Methods. 2007 4(11) 931-6
    Production of complex nucleic acid libraries using highly parallel in situ oligonucleotide synthesis.

    Cleary MA, Kilian K, Wang Y, Bradshaw J, Cavet G, Ge W, Kulkarni A, Paddison PJ, Chang K, Sheth N, Leproust E, Coffey EM, Burchard J, McCombie WR, Linsley P, Hannon GJ.

    Nature Methods. 2004 1(3) 241-8
    Effects of atmospheric ozone on microarray data quality.

    Fare TL, Coffey EM, Dai H, He YD, Kessler DA, Kilian KA, Koch JE, LeProust E, Marton MJ, Meyer MR, Stoughton RB, Tokiwa GY, Wang Y.

    Analytical Chemistry. 2003 75(17) 4672-5
    A flexible light-directed DNA chip synthesis gated by deprotection using solution photogenerated acids.

    Gao X, LeProust E, Zhang H, Srivannavit O, Gulari E, Yu P, Nishiguchi C, Xiang Q, Zhou X.

    Nucleic Acids Research. 2001 29(22) 4744-50.
    Characterization of oligodeoxyribonucleotide synthesis on glass plates.

    LeProust E, Zhang H, Yu P, Zhou X, Gao X.

    Nucleic Acids Research. 2001 29(10) 2171-80
    Unexpected formation of parallel duplex in GAA and TTC trinucleotide repeats of Friedreich’s ataxia.

    LeProust EM, Pearson CE, Sinden RR, Gao X.

    Journal of Molecular Biology. 2000 302(5) 1063-80
    Digital light-directed synthesis. A microarray platform that permits rapid reaction optimization on a combinatorial basis.

    LeProust E, Pellois JP, Yu P, Zhang H, Gao X, Srivannavit O, Gulari E, Zhou X.

    Journal of Combinatorial Chemistry. 2000 2(4) 349-54
  • Patrick Finn

    President and Chief Operating Officer

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    Patrick Finn

    President and Chief Operating Officer

    Patrick a une solide expérience des ventes à forte croissance dans des organisations de bioréactifs, B2B et de fabrication sur mesure. Ses antécédents techniques associés à sa capacité à identifier les besoins encore non satisfaits des clients font de lui la personne idéale pour diriger notre organisation commerciale. Avant de travailler pour Twist Bioscience, Patrick a été vice-président des ventes et du marketing d’Enzymatics (récemment racheté par QIAGEN). Il a dirigé les activités commerciales pour l’Amérique du Nord et l’Europe, a permis une croissance importante de la gamme principale et a développé la base de clients B2B. Avant d’entrer chez Enzymatics, il a occupé des postes de plus en plus centrés sur l’aspect commercial, notamment ceux de directeur du développement commercial chez Agilent Technologies, de directeur du développement de produit pour Beckman Coulter Molecular Diagnostics et divers rôles techniques dans le domaine du développement de produit chez Invitrogen et GE Healthcare/Amersham International. En outre, Patrick siège actuellement au conseil consultatif scientifique de Lasergen après avoir siégé précédemment au conseil consultatif scientifique d’Enzymatics. Il a obtenu un doctorat (PhD) en chimie des acides nucléiques de l’Université de Southampton et un baccalauréat ès sciences (avec félicitations) de chimie de l’Université Heriot-Watt.

  • Adam Laponis

    DIRECTEUR FINANCIER

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    Adam Laponis

    DIRECTEUR FINANCIER

    Adam has deep financial acumen and strategic planning expertise across diverse businesses along with a track record of collaborating across teams to drive profitable growth. Prior to joining Twist, Adam served as chief financial officer of Eargo, Inc., where he was responsible for finance, accounting, investor relations, business operations, internal audit and information technology. During his tenure at Eargo, revenue increased more than 300% over the course of two years. Prior to Eargo, Adam was vice president, worldwide financial planning and analysis and business operations at Tesla, Inc. where he was responsible for worldwide pricing, forecasting, capital planning, development of internal controls, and optimization of business operations. Previously, Adam served as vice president, finance and chief financial officer, cardiovascular care at Cardinal Health as the finance leader for the worldwide Cordis Cardiovascular business. He held a series of roles of increasing responsibility at Johnson & Johnson, where he led the divestiture of Cordis to Cardinal Health. He held additional positions within Johnson & Johnson including controller of the diabetes franchise, manager of supply chain and quality finance and customer service finance. Adam holds an MBA from the University of Southern California, Marshall School of Business and a B.S. in chemical engineering from the University of California at Berkeley.

  • Nicole Moreno
    Nicole Moreno

    Senior Vice President of Sales and Support

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    Nicole Moreno

    Nicole Moreno

    Senior Vice President of Sales and Support

    Nicole is a visionary sales leader with over 17 years of experience driving commercial success within NGS, synthetic biology, molecular diagnostics and RNA therapeutics. She has a proven track record of building and coaching high-performing sales teams at local, national and global levels, and implementing innovative sales methodologies to meet evolving customer needs. Since joining Twist in 2020, Nicole has consistently delivered high growth sales across various vertical markets, serving in escalating positions within the commercial team. She was appointed SVP of Sales and Support in October 2024.

    Before Twist Bioscience, Nicole held multiple leadership roles within the North America Custom Solutions & OEM sales teams at QIAGEN. During her tenure at QIAGEN, she successfully led the North American sales teams to achieve more than double team sales in 3 years and was recognized as a QIAGEN President's Circle Award Winner. Previously, Nicole served in senior sales roles at Enzymatics (a QIAGEN company), where she expanded the Western Region by driving customer and revenue growth through new business opportunities. Prior to Enzymatics, Nicole held positions at Affymetrix and USB Corporation where she substantially increased revenue growth through strategic account management and business development.

    Nicole holds a B.S. in Biochemistry from Colorado State University.

  • Siyuan Chen
    Siyuan Chen

    Directeur général de la technologie

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    Siyuan Chen

    Siyuan Chen

    Directeur général de la technologie

    Le Dr Chen est un spécialiste de la pensée stratégique, fort d’une expérience avérée en matière d’identification, de développement et de commercialisation de produits dans les domaines de la NGS, de la biologie de synthèse et d’autres sciences de la vie. Il a rejoint Twist peu après la création de l’entreprise et dirige le développement de produits pour les gammes de produits de biologie de synthèse et de NGS. Le Dr Chen a conçu et mis en œuvre une nouvelle gamme de produits pour NGS qui inclut des contrôles synthétiques pour le SARS-CoV-2 et d’autres maladies infectieuses. Il a développé des biochimies, processus, kits de réactifs et infrastructures de synthèse de gène et d’enrichissement de cibles pour NGS. Il a également élaboré le prototype de synthétiseur d’ADN de l’entreprise avec la collaboration d’ingénieurs en matériel, logiciels et silicone, lequel synthétiseur est ensuite devenu une machine de production au service de la technologie de base de Twist. Le Dr Chen est l’auteur de nombreux articles vérifiés par des pairs et il a déposé des brevets dans le domaine de la synthèse des oligonucléotides et l’application des oligonucléotides synthétiques. Il a obtenu son doctorat (Ph.D.) en chimie à l’Université du Winconsin (Madison) et un une maîtrise ès sciences (B. Sc.) en chimie à l’Université de Pékin, en Chine. 

  • Paula Green

    Vice-présidente senior des Ressources humaines

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    Paula Green

    Vice-présidente senior des Ressources humaines

    Paula Green est un cadre expérimenté dans le domaine des Ressources humaines avec une expérience avérée en matière de développement et de mise à disposition de stratégies, solutions, processus et outils de ressources humaines à fort impact qui soutiennent les compétences de leadership pour permettre à l’organisation d’être hautement performante. Avant de rejoindre Twist Bioscience, elle a occupé le poste de vice-présidente, responsable des Ressources humaines, chez QIAGEN. Dans cette fonction, elle a supervisé 50 professionnels des ressources humaines intervenant auprès de 4 000 employés par le biais de fusions, d’acquisitions, de restructurations et d’autres transactions d’entreprise essentielles. Elle a dirigé le service des Ressources humaines d’Operon Technologies (acquis par QIAGEN). Parmi ses responsabilités figuraient la création de la stratégie, la supervision des avantages sociaux de tous les employés et l’application des programmes de formation, de recrutement et de fidélisation.  Elle a également travaillé en tant que consultant en ressources humaines pour la Federal Home Loan Bank de San Francisco. Paula possède une maîtrise en sciences (BS) en comportement organisationnel délivré par l’Université de San Francisco. 

  • Mike Fero
    Mike Fero

    Chief Information Officer

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    Mike Fero

    Mike Fero

    Chief Information Officer

    Mike is a seasoned executive with experience leading startups, developing commercial software, researching biology and physics and working in fast-paced deep-tech businesses.

    Before joining Twist, he co-founded and served as CEO of TeselaGen Biotechnology for a decade, where he spearheaded TeselaGen’s enterprise software platform, providing a comprehensive suite of tools for DNA design, assembly, management and experimental workflows to a range of biotech customers from startups to Fortune 50 companies. Prior to TeselaGen, he was a principal investigator and NIH Career Fellow at Stanford University where he explored the signaling pathways that govern the bacteria cell cycle through the development of an automated epifluorescence microscopy platform including both hardware and software for high-throughput, high-content genetic screens and subsequent data analysis. He also served as director of Stanford Functional Genomics, where he collaborated on the development of the first human and murine genome scale microarrays. Prior to Stanford, Mike served as vice president of software engineering at Neomorphic where he guided development of a laboratory information management system (LIMS) solution for the human genome project at Lawrence Berkeley National Laboratory. Before Neomorphic, he held a variety of escalating positions at HyperParallel and Massachusetts Institute of Technology. 

    Mike holds a Ph.D. in Physics and a B. A. in both Math and Physics, both from the University of California, Irvine. He completed a postdoctoral fellowship at the Massachusetts Institute of Technology, Cambridge and conducted international studies in Maths at Trinity College, Dublin. He serves as an advisor to both government and private groups exploring the promise, limits and concerns around the field of synthetic biology.

    Publications
    • Fero MJ, Craft JK, Vu T, Hillson NJ. Combinatorial-Hierarchical DNA Library Design Using the TeselaGen DESIGN Module with j5. Methods Mol Biol. 2020;2205:19-47.
    • Zhang J, Petersen SD, Radivojevic T, Ramirez A, Pérez-Manríquez A, Abeliuk E, Sánchez BJ, Costello Z, Chen Y, Fero MJ, Martin HG, Nielsen J, Keasling JD, Jensen MK. Combining mechanistic and machine learning models for predictive engineering and optimization of tryptophan metabolism. Nat Commun. 25 sept. 2020;11(1):4880.
    • “HEEBO and MEEBO Chips – Human and Mouse Exonic Evidence-Based Oligonucleotide Reporters for Microarray Based Expression Analysis,” Keystone Symposia Conference, Systems Biology: Integrating Biology, Technology and Computation, 5 mars 2006.
    • Plahar HA, Rich TN, Lane SD, Morrell WC, Springthorpe L, Nnadi O, Aravina E, Dai T, Fero MJ, Hillson NJ, Petzold CJ. BioParts-A Biological Parts Search Portal and Updates to the ICE Parts Registry Software Platform. ACS Synth Biol. 15 oct. 2021;10(10):2649-2660.
    • Goyal G, Elsbree N, Fero M, Hillson NJ, Linshiz G. Repurposing a microfluidic formulation device for automated DNA construction. PLoS One. 11 nov. 2020;15(11):e0242157.
    • Cable J, Leonard JN, Lu TK, Xie Z, Chang MW, Fernández LÁ, Lora JM, Kaufman HL, Quintana FJ, Geiger R, F Lesser C, Lynch JP, Hava DL, Cornish VW, Lee GK, DiAndreth B, Fero M, Srivastava R, De Coster T, Roybal KT, Rackham OJL, Kiani S, Zhu I, Hernandez-Lopez RA, Guo T, Chen WCW. Synthetic biology: at the crossroads of genetic engineering and human therapeutics-a Keystone Symposia report. Ann N Y Acad Sci. déc. 2021;1506(1):98-117.
    • Hodgson, A., Alper, J., Maxon, M.E. 2022. The U.S. Bioeconomy: Charting a Course for a Resilient and Competitive Future. New York, New York: Schmidt Futures. doi.org/10.55879/d2hrs7zwc.
    • Eichenbaum, A., Miłowski, A., Beverly, A., Fero, M., Downs, M., Treynor, T., Gibbons, S., Venayak, N., Densmore, D., Provencher, L., Veeramalla, R., Yan, H., Lee, H., Stamps, B., Dobbs, T., Cheng, M., Dunlap, C., Ly, K., Saryan, L. 2024. Data Modeling and Coding Standards. BioMADE Digital Infrastructure Committee (unpublished).
    • B Christen,* MJ Fero,* NJ Hillson, G Bowman, S-H Hong, L Shapiro, HH McAdams: High throughput identification of protein localization dependency networks. Proceedings of the National Academy of Sciences USA 2010, 107(10):4681-4686. *equal contribution.
    • Fero M, Pogliano K. Automated quantitative live cell fluorescence microscopy. Cold Spring Harbor perspectives in biology. 1er août 2010;2(8):a000455.
    • Fero M, Christen B, Hillson N, Bowman G, Hong S, Shapiro L, McAdams H. Illuminating complete functional networks: Automation, computation and the single cell F1000research. 1. doi: 10.7490/F1000Research.367.1 
    • Christen B, Abeliuk E, Collier JM, Kalogeraki V, Passarelli B, Coller JA, Fero MJ, McAdams HH, Shapiro L: The Essential Genome of a Bacterium, Molecular Systems Biology 2011, 7(528).
    • Umbarger MA, Toro E, Wright MA, Porreca GJ, Baù D, Hong SH, Fero MJ, Zhu LJ, Marti-Renom MA, McAdams HH, Shapiro L, Dekker J, Church GM. The three-dimensional architecture of a bacterial genome and its alteration by genetic perturbation. Mol Cell. 21 oct. 2011;44(2):252-64.
    • K Abe, et al: An improved measurement of the left-right Z0 cross-section asymmetry. Physical Review Letters 1997, 78:2075-2079.
  • Mark Buck

    Senior Vice President of Operations

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    Mark Buck

    Senior Vice President of Operations

    Mark is experienced in improving manufacturing efficiency and driving revenue and margin through managing supply chain and operations, including planning, quality, procurement and logistics. Prior to joining Twist, Mark served as corporate senior vice president, operations, global supply chain at Excelitas Technologies Corporation where he established a global footprint, drove global supply chain optimization measures, enabled scale up and drove revenue growth. His responsibilities included global supply chain planning, global sourcing and procurement supply, internal supply, supply quality and logistics inbound and outbound movement of freight. Prior to Excelitas, Mark was director, global supply chain management and general manager of resale product operations at Bio-Rad, Inc., where he managed buy-sell products, which grew in revenue to $270 million, significantly improving profitability over his time in the role. He previously held leadership positions including vice president operations, global manufacturing, supply chain and logistics at Celerity Group; director, operations management at Solectron corporation; and senior supply chain operations manager at Apple Computer, Inc. Before joining industry, Mark served in the United States Marine Corps. He holds an MBA from National University and a B.S. in electrical and computer engineering from University of Illinois, Urbana-Champaign.

  • Bill Banyai, PhD

    Vice-président senior du développement avancé et directeur général, Stockage de données

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    x

    Bill Banyai, PhD

    Vice-président senior du développement avancé et directeur général, Stockage de données

    Bill est un entrepreneur chevronné et un expert en matière d’ingénierie du silicone. Il a été le fondateur ou le premier employé de quatre start-up différentes et il fournit des conseils sur les débuts des start-up. En sa qualité de VP de l’ingénierie hardware chez Complete Genomics, il a élaboré la technologie de séquençage de l’entreprise et produit trois générations de pastilles et séquenceurs de génome humain. Bill s’est vu deux fois attribuer des subventions de plusieurs millions de dollars par l’agence DARPA pour le développement de technologies innovantes basées sur le micro-usinage du silicium. La carrière de Bill s’étend aux domaines de la recherche, du développement de produit et du traitement d’appareils à semiconducteurs. Il a obtenu un doctorat (PhD) en sciences optiques de l’Université de l’Arizona et un master ès sciences (MS) en science électrique de l’Université du Michigan, et il a travaillé en tant que physicien permanent au Lawrence Livermore National Laboratory.

    Publications
    Human Genome Sequencing Using Unchained Base Reads on Self-Assembling DNA Nanoarrays.

    Drmanac R, Sparks AB, Callow MJ, Halpern AL, Burns NL, Kermani BG, Carnevali P, Nazarenko I, Nilsen GB, Yeung G, Dahl F, Fernandez A, Staker B, Pant KP, Baccash J, Borcherding AP, Brownley A, Cedeno R, Chen L, Chernikoff D, Cheung A, Chirita R, Curson B, Ebert JC, Hacker CR, Hartlage R, Hauser B, Huang S, Jiang Y, Karpinchyk V, Koenig M, Kong C, Landers T, Le C, Liu J, McBride CE, Morenzoni M, Morey RE, Mutch K, Perazich H, Perry K, Peters BA, Peterson J, Pethiyagoda CL, Pothuraju K, Richter C, Rosenbaum AM, Roy S, Shafto J, Sharanhovich U, Shannon KW, Sheppy CG, Sun M, Thakuria JV, Tran A, Vu D, Zaranek AW, Wu X, Drmanac S, Oliphant AR, Banyai WC, Martin B, Ballinger DG, Church GM, Reid CA.

    Science. 2010 327(5961) 78-81
    Modular MEMS design and fabrication for an 80 x 80 transparent optical cross-connect switch.

    Fernandez A, Staker BP, Owens WE, Muray LP, Spallas JP, Banyai WC.

    Proceedings SPIE - Optomechatronic Micro/Nano Components, Devices, and Systems. 2004 5604 208-217
    Scaling behavior in interference lithography.

    Agayan RR, Banyai WC, Fernandez AJ.

    Proceedings SPIE - Emerging Lithographic Technologies II. 1998 3331 662-672
    Time-to-frequency converter for measuring picosecond optical pulses.

    Kauffman MT, Banyai WC, Godil AA, Bloom DM.

    Applied Physics Letters. 1994 64(3) 270-272
    Applications of time lens optical systems.

    Kauffman MT, Godil AA, Auld BA, Banyai WC, Bloom DM.

    Electronics Letters. 1993 29(3) 268-269
    Interaction of super-intense light fields with atoms and surfaces.

    Downer MC, Banyai WC, Wood WM, Anacker DC, Erskine JL.

    Proceedings SPIE - Picosecond and Femtosecond Spectroscopy from Laboratory to Real World. 1990 1209 166-174
    Spectral shifting of femtosecond pulses in atmospheric density plasmas.

    Spectral shifting of femtosecond pulses in atmospheric density plasmas.

     
    Picosecond pump-probe interferometric measurement of optical nonlinearities in channel waveguides.

    Finlayson N, Banyai WC, Seaton CT, Stegeman GI, O'Neill M, Cullen TJ, Ironside CN.

    Optics Letters. 1989 14(10) 532-534
    Optical nonlinearities in CdSxSe1-x-doped glass waveguides.

    Finlayson N, Banyai WC, Seaton CT, Stegeman GI, O'Neill M, Cullen TJ, Ironside CN.

    Journal of the Optical Society of America B: Optical Physics. 1989 6(4) 675-684
    Saturation of the nonlinear refractive-index change in a semiconductor-doped glass channel waveguide.

    Banyai WC, Finlayson N, Seaton CT, Stegeman GI, O’Neill M, Cullen TJ, Ironside CN.

    Applied Physics Letters. 1989 54(6) 481-483
    Observation of ultrafast nonlinear polarization switching induced by polarization instability in a birefringent fiber rocking filter.

    Trillo S, Wabnitz S, Banyai WC, Finlayson N, Seaton CT, Stegeman GI, Stolen RH.

    IEEE Journal of Quantum Electronics. 1989 25(1) 104-112
    Picosecond switching induced by saturable absorption in a nonlinear directional coupler.

    Finlayson N, Banyai WC, Wright EM, Seaton CT., Stegeman GI, Cullen TJ, Ironside CN.

    Applied Physics Letters. 1988 53(13) 1144-1146
    Picosecond nonlinear polarization switching with a fiber filter.

    Trillo S, Wabnitz S, Finlayson N, Banyai WC, Seaton CT, Stegeman GI, Stolen RH.

    Applied Physics Letters. 1988 53(10) 837-839
    Nonlinear-optical effects in ion-exchanged semiconductor-doped glass waveguides.

    Ironside CN, Cullen TJ, Bhumbra BS, Bell JA, Banyai WC, Finlayson N, Seaton CT, Stegeman GI.

    Journal of the Optical Society of America B: Optical Physics. 1988 5(2) 492-495
    High-speed intensity-dependent refractive index in semiconductor-doped glasses.

    Seaton CT, Stegeman GI, Yao SS, Karaguleff C, Fortenberry R, Gabel A, Banyai W, Assanto G.

    Proceedings SPIE - Advances in Materials for Active Optics. 1985 567 132
  • Directeur ESG, Vice-président senior des affaires générales
    Angela Bitting

    Directeur ESG, Vice-président senior des affaires générales

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    Directeur ESG, Vice-président senior des affaires générales

    Angela Bitting

    Directeur ESG, Vice-président senior des affaires générales

    En sa qualité de cadre senior en communications, forte de plus de 25 ans d’expérience dans l’industrie biopharmaceutique, Angela excelle dans la création de messages clairs et de communications cohérentes qui accroissent la visibilité parmi les principales parties prenantes, et dans la diffusion de la culture et de la communication dans l’ensemble de l’entreprise. Avant de rejoindre Twist, elle a dirigé son propre cabinet de conseils pendant 20 ans au service de clients dans les domaines biopharmaceutique, des dispositifs médicaux et du diagnostic afin de créer des messages favorisant une communication efficace auprès du public externe. Avant de créer son propre cabinet de conseils, Angela a dirigé le services des relations avec les investisseurs et des communications d’entreprise d’Exelixis, Inc. Elle a passé plusieurs années chez Russell-Welsh, Inc., une agence-boutique de communications en matière de soins de santé, ce qui l’a amenée à travailler avec tout un éventail de clients publics et privés sur une large gamme de services de communications. Elle a obtenu un baccalauréat ès sciences en biologie cellulaire et moléculaire et un baccalauréat ès arts en marketing commercial de l’Université de Washington. Elle occupe actuellement le poste de VP des provisoires de la section locale de la National Charity League.

  • Dennis Cho

    Chief Legal Officer and Corporate Secretary

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    x

    Dennis Cho

    Chief Legal Officer and Corporate Secretary

    Dennis Cho is a seasoned in-house business attorney with a proven track record of agile strategic guidance and practical problem solving. Prior to Twist, he served as assistant general counsel at CytomX Therapeutics, where he was department head for all deals and contracts as well as day-to-day lead on compliance and numerous other legal subject matters. Prior to CytomX, Mr. Cho was the lead transactional attorney on antibody-related licenses and collaborations, major commercial agreements, and combination trials at Seattle Genetics. Before that, he spent nine years at Celgene as the lead West Coast attorney supervising over 100 business transactions, including in- and out- licenses, options, collaborations and M&A agreements, and held primary legal responsibility for Celgene’s alliances, equity investments and “big data” machine learning initiative. Prior to Celgene, Mr. Cho served as general counsel for four private and public companies. He earned his J.D. and a B.A. in Molecular Cell Biology (Genetics) from University of California, Berkeley.

Équipe

Conseil

Rob Chess

Président du conseil d’administration
Nektar Therapeutics

Nelson C. Chan

Président du conseil
Synaptics et Adesto

Keith Crandell

Co-fondateur et directeur général
Arch Venture Partners

Jan Johannessen

Conseiller auprès d’iGlobe Partners

Xiaoying Mai

Head of Private Equity, GF Investments (Hong Kong) Company Limited

Bob Ragusa

CEO
GRAIL, LLC

Melissa Starovasnik, Ph.D.

Former Vice President, Protein Sciences and Head of Large Molecule Drug Discovery
Genentech

Emily Leproust

Présidente directrice générale
Twist Bioscience

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