Writing the Future of Antibody Engineering
Unlocking the potential of antibody improvement has never been more exciting. With Twist Bioscience's innovative DNA writing technologies, we're redefining what's possible in antibody discovery and development.
At Twist Biopharma Solutions, we’re revolutionizing antibody engineering and optimization with high-throughput, silicon-based technology to enable rapid, precise creation of custom antibody libraries tailored to enhancing your therapeutic antibody candidates. Complemented by our AI/ML engine and state-of-the-art antibody characterization capabilities, we can deliver antibody candidates with the greatest chance of clinical success. Learn more about how our partnership can empower your biotherapeutics breakthroughs and beyond.
Key Features
Unmatched Scale
速度与效率
Diversity and Precision
定制化
Iterative Optimization
The Twist Antibody Optimization (TAO) Toolbox at your Fingertips
Discover more with a comprehensive suite of tools and services for antibody engineering and optimization. Our TAO platform offers the scientific expertise of our antibody engineers with innovative technologies to accelerate your biologic discovery and development.
Custom Library Generation
Simply input your murine, chimeric, humanized, or fully human antibody sequence, and our algorithm will optimize and humanize it into a “human repertoire-inspired” phage display library.
- pH-Dependent Binding
- Liability Mitigation
- Improve Biophysical Properties
- Optimize Kinetic Profile
- Strengthen IP Filings or FTO Lockdown
In Silico Humanization
An add-on or stand-alone service to engineer fully-human antibodies while maintaining desired affinity, safety, and efficacy profiles.
- 物种交叉反应性
- Liability Mitigation
AI/ML-Assisted Language Model Affinity Maturation
Rapid, high-diversity in silico library screening to deliver you a selection of antibody variants with improved affinity profile.
- Affinity Maturation
- Liability Mitigation
- Improve Biophysical Properties
Are you looking for a specific application or interested in designing a
custom program with our antibody engineers?
听听科学家们怎么说
Twist 是唯一能够按照我们项目所要求的数量和质量标准快速交付 DNA 的合成 DNA 供应商。我们之间的合作不仅限于提供合成基因和抗体，还进一步得到了深化，有助于我们更好地使用 Twist Biopharma 的产品，我们相信这将完善我们的抗体发现工作。”
Robert Carnahan 博士
Vanderbilt 疫苗中心副主任
我们的平台迅速生成并验证治疗具有挑战性的癌症的新靶点。与 Abveris 协作将使我们能够快速识别并选择针对这些靶点的高度特异性抗体，这样我们就可以开发出最好的抗体，以满足特定患者群体的需求。”
首席执行官 JEFF GOLDBERG
Immunitas Therapeutics
联系我们
我们的抗体专家随时待命，并希望听到更多关于您的发现需求的信息。欢迎挑战性目标！
