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Product Sheet
Twist Bioscience HQ
681 Gateway Blvd
South San Francisco, CA 94080
Variant Libraries
Access to Expertise
Our years of molecular biology expertise combined with the Twist DNA Synthesis Silicon platform ensures that you receive the exact library you want with no compromises.
Complex Custom Libraries
Twist’s proprietary oligo synthesis technology offers a unique approach to library creation. The silicon-based synthesis platform generates high-quality oligo pools, which are used to build fully-customized, user-defined variant libraries on a single chip. Twist's unparalleled platform also enables the creation of thousands to billions of specific variants. You can be assured exactly what you design is exactly what you get.
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High Diversity Variant Domains
Twist has developed high fidelity methods for precisely splicing large pools of oligonucleotides (with composition and length variation) to create NGS verified combinatorial diversity of up to 10^10 unique variants within a single domain. Every variant is designed in-silico and screened prior to synthesis, eliminating unwanted sequence bias, premature stop codons, and undesirable motifs.
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Learn more about Libraries Technology
What Scientists Have to Say
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The Library we’ve asked for was very complex. Based on our analysis, the library we received was excellent. What we’ve designed is what we’ve obtained.
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Working with Twist was a great experience. Twist’s support was amazing. We have performed the first validation selections which looks promising.
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We have performed the first selections using the Fab and scFv libraries. No problem in both cases, we got clones and some look really promising.
Finally, an easy way to order DNA
Instantly know if your sequence is a go
Our smart algorithm lets you know in seconds if your sequence can be synthesized or not
Your quote is now just one click away
No more wasted time waiting for surprise quotes. See real-time pricing when you submit your data
Stay in the know from checkout to your door
We update you at every stage of your order’s progress, giving you comprehensive insight on crucial production details
Intuitive usability meets bulletproof security
Upload your sequences with the comfort of knowing your proprietary data is protected
