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Complex motifs we support

 

Twist's Gene Synthesis platform offers you the best shot to make every gene sequence you need in predictable timescales. See which complex motifs we can support below, or sign in to immediately verify your sequence.

Short Tandem Repeats

Regions of 3-9 bp that repeat multiple times, with up to 100% homology between repeats.


We support short tandem repeats spanning up to 100 bp.
Long Repeats

Regions ≥10 bp with up to 100% homology that repeat more than once within a single sequence.
Inverted Repeats (Hairpins)

Repeats complementary to each other, with up to 100% homology between repeats.
Extreme localized GC content

Local GC content within 50bp regions.
Homopolymers

Runs of an identical base.
High/low average GC content

GC content across the whole sequence.

 
Start your order

Product data

Complex DNA. Simple pricing.

All Gene products are USA-made, shipping globally from our factory in Wilsonville, OR. Here, our scientists use ultra-long oligo synthesis on silicon, automated enzymatic assembly, and long-read sequencing to produce your Complex Gene Synthesis projects.

See pricing

US manufacturing

All Gene products are USA-made, shipping globally from our factory in Wilsonville, OR. Here, our scientists will use ultra-long oligo synthesis on silicon, automated enzymatic assembly, and long-read sequencing to produce your Complex Gene Synthesis projects.

Reliable turnaround

For Complex Genes, we provide estimated turnaround time before you order as well as live manufacturing tracking on our portal. We aim to complete all Complex Gene orders within 15 business days. We will contact you immediately should challenges arise.

Support from real scientists

Twist’s Technical Support team is available to help you tackle your biggest research challenges. If you ever have a question or issue, click on the chat icon in the bottom-right of our website, and connect with a real scientist in minutes.

Product data

Complex DNA. Simple pricing.

Manage projects with predictable costs. While Complex Genes cost a little more than standard gene synthesis, we don't change our cost-per-base on a per-sequence basis. Get an immediate quote for your Complex Genes order in our ordering portal.

See pricing

US manufacturing

All Gene products are USA-made, shipping globally from our factory in Wilsonville, OR. Here, our scientists use ultra-long oligo synthesis on silicon, automated enzymatic assembly, and long-read sequencing to produce your Complex Gene Synthesis projects.

Reliable turnaround

For Complex Genes, we will provide estimated turnaround time before you order as well as live manufacturing tracking on our portal. We will aim to complete all Complex Gene orders within 15 business days. We will contact you immediately should challenges arise.

Support from real scientists

Twist's Technical Support team is available to help you tackle your biggest research challenges. If you ever have a question or issue, click on the chat icon in the bottom-right of our website, and connect with a real scientist in minutes.

Start your order

What our customers say

"A key part of our work with external partners is keeping to our agreed project delivery timelines. Having a reliable synthesis partner in Twist is a huge factor in the success of this work, as they make it easy to track the progress of my order, deliver genes on time, and actively communicate whenever there is an issue."

Imogen Binnan, PhD
Lead Biologist, Resurrect Bio

"The online ordering experience on Twist is by far the smoothest and most delightful of all providers I have tried. Together with the competitive pricing, Twist is our team's go-to supplier for DNA Fragments, Clonal Genes, and Oligo pools."

David Lips
Frontier Development, Spiber Inc.

"I am a structural biologist working on proteins with diverse functions from a wide range of organisms. Our research requires extensive gene screening, and therefore gene synthesis must be accurate, fast, and cost-effective. Genes synthesized by Twist Bioscience have consistently shown a low error rate and reliable quality, while being delivered rapidly and at a reasonable cost. We look forward to continuing to work with Twist Bioscience in the future."

Masahiro Fukuda, Ph.D.
Assistant Professor, The Research Center for Advanced Science and Technology (RCAST)

*Results are specific to the institution where they were obtained and may not reflect the results achievable at other institutions

Simple, transparent ordering for Complex Genes

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Upload and review your sequences

We analyze your sequences for manufacturability. Modify your sequences if needed. Immediate pricing and turnaround estimates are provided.

How it works
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Customize your order

Choose your prep scale, endotoxin level, required quality documentation, normalization and delivery form

How it works step 2
Checkout and receive your Complex Genes

Generate a quote and check out. Track your order in real time as it is manufactured. If there is an issue, hear from one of our DNA experts immediately.

How it works step 3
Start your order

Twist Bioscience HQ
681 Gateway Blvd
South San Francisco, CA 94080