The Baker Lab at the University of Washington: Designing Proteins to Revolutionize Biotechnology

Oligo pools allow The Baker Lab to screen thousands of potentially viable designs to construct proteins that have never existed in nature.

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The Baker Lab is part of the Institute for Protein Design at the University of Washington. Instead of engineering an existing protein sequence, the lab focuses on the design of entirely new proteins to address challenges in health and technology. This case study discusses how Twist Oligo Pools enable the Baker Lab to achieve higher success rates than ever before, focusing on two recent studies that produced new proteins for neutralizing the virulence factors causing botulism and influenza.

Covered in this Case Study

How the Baker Lab interrogate protein folding with Oligo Pools

How Oligo Pools have enhanced their experimental success rate

How these benefits are applied to the design on new therapeutic proteins.

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Genes

Oligo Pools

NGS Target Enrichment Solutions

Variant Libraries

Synthetic Controls

Antibody Discovery

The Baker Lab at the University of Washington: Designing Proteins to Revolutionize Biotechnology

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