A Cost-Effective Pan-Genome-Based Platform for Genotype Imputation, QTL Mapping, and Breeding Support

Josh Clevenger, Ph.D.
Presented by
Josh Clevenger, Ph.D.
Josh Clevenger, Ph.D.
HudsonAlpha Institute for Biotechnology, Faculty Investigator

Covered in this Webinar
Dive into the science behind Twist’s FlexPrep™ and how it streamlines sample preparation for high-throughput genomics.
Get a live look at how pan-genome graphs unlock insights that linear references miss.
See how enrichment panels are replacing traditional arrays—offering flexibility, deeper data, and more insights on key variants.

In this presentation from The Landscape of Cancer Research: Advances in Immuno-Oncology, Twist Bioscience highlights a multifaceted approach to antibody discovery targeting Dickkopf-1 (DKK1), a protein implicated in tumor progression and immune evasion. The talk, titled “Identification of Dickkopf-1 (DKK1) Antibodies Utilizing a Multi-Faceted Discovery Strategy,” outlines how Twist’s synthetic DNA and antibody libraries enabled the rapid development of high-affinity antibodies with therapeutic potential.

The presentation showcases how Twist’s platform integrates high-throughput screening, precision gene synthesis, and rational design to accelerate the development of novel immunotherapies. By targeting DKK1—a promising but challenging cancer antigen—Twist demonstrates the power of its end-to-end antibody discovery workflow for advancing immuno-oncology research and supporting the development of next-generation cancer therapies.

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