Functional Cell-Based Assays

Biological activity and determining the MoA for your lead antibodies can be the final step before moving into in vivo testing.


Twist Biopharma Solutions’ scientific experts use off-the-shelf or can develop custom cell-based assays to put your biochemical and biophysical data in context. Along with our high-throughput antibody expression and robust portfolio of characterization services and exceptional track record, we can help you make an informed decision about which leads will give you the greatest chance of preclinical success.

Specialized Immune Assays

We also conduct specialized immune assays for T-cell, B-cell, dendritic cell, natural killer cell, and macrophage: Our functional assays team can also develop a custom assay that fits your program’s needs.

Complementary Services for Therapeutic Antibody Development

Antibody production, affinity assessment, epitope binning, and developability assessment play crucial roles alongside the functional testing of a candidate antibody. Twist offers these services as an integrated end-to-end discovery workflow or as a standalone service, providing you with the format that fits your needs best. Together, these services create a comprehensive picture of an antibody's therapeutic potential, guiding you toward the most promising candidates for preclinical and clinical studies.