Start Your Discovery Campaign on the Right Foot
The quality of an antigen is critical to the success of every in vivo antibody discovery project. We built our antigen production capabilities to offer a reliable source of high-quality reagents and give our partners flexibility without sacrificing a streamlined workflow.
Twist’s Molecular Biology team has years of experience generating reagents for antibody discovery campaigns. We have optimized and proprietary techniques that generate robust immune responses for difficult target classes. Additionally, we can leverage our proprietary DiversimAb™ platform to induce immune responses against poorly immunogenic targets and improve antibody discovery timelines and success rates.
Start Your Discovery Campaign on the Right Foot
The quality of an antigen is critical to the success of every in vivo antibody discovery project. We built our antigen production capabilities to offer a reliable source of high-quality reagents and give our partners flexibility without sacrificing a streamlined workflow.
Twist’s Molecular Biology team has years of experience generating reagents for antibody discovery campaigns. We have optimized and proprietary techniques that generate robust immune responses for difficult target classes. Additionally, we can leverage our proprietary DiversimAb™ platform to induce immune responses against poorly immunogenic targets and improve antibody discovery timelines and success rates.
Immunization Expertise for any Antigen
Access Difficult-to-Express Antigens
Twist utilizes proprietary immunization vectors to directly express target antigens in mice, facilitating antibody discovery for challenging targets such as GPCRs and multi-spanning membrane proteins, and saving on antigen production costs and time. We can also leverage cell-based and subtractive immunization to enrich responses to cell-surface antigens.
Guidance from Antigen and Immunization Experts
The benefits of working with Twist include an experienced protein sciences team that reviews antigens and recommends critical sequence modifications before expression, optimized systems for rapid, ultra-high-yield protein production, high-level expression with appropriate post-translational modifications, and integrated antibody discovery capabilities.
Quick and Efficient Cell Line Generation
Our transient cell line generation approach allows our partners to quickly and efficiently succeed in their mAb discovery campaigns.
Rapidly Access 1000s of Off-the-Shelf Antigens
Thousands of recombinant protein antigens for popular targets are available on expedited timelines, so you can get your antibody discovery program going as quickly as possible.
Immunization Expertise for any Antigen
Access Difficult-to-Express Antigens
Twist utilizes proprietary immunization vectors to directly express target antigens in mice, facilitating antibody discovery for challenging targets such as GPCRs and multi-spanning membrane proteins, and saving on antigen production costs and time. We can also leverage cell-based and subtractive immunization to enrich responses to cell-surface antigens.
Guidance from Antigen and Immunization Experts
The benefits of working with Twist include an experienced protein sciences team that reviews antigens and recommends critical sequence modifications before expression, optimized systems for rapid, ultra-high-yield protein production, high-level expression with appropriate post-translational modifications, and integrated antibody discovery capabilities.
Quick and Efficient Cell Line Generation
Our transient cell line generation approach allows our partners to quickly and efficiently succeed in their mAb discovery campaigns.
Rapidly Access 1000s of Off-the-Shelf Antigens
Thousands of recombinant protein antigens for popular targets are available on expedited timelines, so you can get your antibody discovery program going as quickly as possible.
Qué dicen los científicos
Title
DR. ROBERT CARNAHAN
Title
Twist es el único proveedor de ADN sintético que puede proporcionar rápidamente la cantidad y calidad de ADN que necesitamos para nuestros proyectos. Estamos trabajando con ellos como proveedor de genes y anticuerpos sintéticos y hemos expandido nuestra relación para aprovechar las capacidades de Twist Biopharma, lo que creemos que complementará nuestros esfuerzos en cuanto al descubrimiento de anticuerpos.
ROBERT CARNAHAN,, PHD
Director asociado del Centro de Vacunas Vanderbilt
Nuestra plataforma genera y valida con rapidez nuevos objetivos para tratar cánceres complejos. Working with Abveris will enable us to quickly identify and select highly specific antibodies for those targets, so that we can take the best antibody forward to address the needs of particular patient populations.
JEFF GOLDBERG,, CEO
Immunitas Therapeutics
Contacte con nosotros
Los entusiastas de los anticuerpos están a su disposición y estarían encantados de saber más sobre sus necesidades de descubrimiento. ¡Son bienvenidos los objetivos complejos!
